Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 7/20 | 0.59 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 6/20 | 0.57 |
| ▸ | CTSL | P07711 | 5/20 | 0.57 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308291 | 0.88 | ATM (0.64) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL8041576 | 0.88 | ATM (0.64) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL22370065 | 0.87 | ATM (0.50) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL11094221 | 0.86 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL2059541 | 0.86 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL5949296 | 0.85 | ATM (0.58) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL4321696 | 0.85 | ATM (0.58) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL7527895 | 0.85 | SYK (0.55) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL6140023 | 0.85 | ATM (0.61) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL17956471 | 0.85 | ATM (0.61) | ATMCTSKCTRB1ELANECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538528-B1 | PYRROLE AMIDES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-12-23 | — | — | EP | disclosed |