Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 2/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.61 |
| ▸ | CTSK | P43235 | 4/20 | 0.61 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ELANE | P08246 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | CTSL | P07711 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041576 | 0.89 | ATM (0.64) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL22753446 | 0.89 | CTSK (0.63) | ATMCTSKCTRB1CYP3A4TSHR | |
| SCHEMBL10612913 | 0.89 | CTSK (0.63) | ATMCTSKCTRB1CYP3A4TSHR | |
| SCHEMBL11515552 | 0.89 | CTSK (0.63) | ATMCTSKCTRB1CYP3A4TSHR | |
| SCHEMBL11094221 | 0.88 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL22808751 | 0.88 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL2059541 | 0.88 | ATM (0.62) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL11514747 | 0.88 | CTSK (0.62) | ATMCTSKCYP3A4TSHRELANE | |
| SCHEMBL17688547 | 0.86 | ATM (0.61) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL241565 | 0.86 | CTSK (0.61) | ATMCTSKCTRB1ELANECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | claimed |
| CN-1036124-A | Plant protection composition | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1989-10-11 | — | — | CN | claimed |
| EP-4522606-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | Merck Sharp & Dohme LLC (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023227006-A1 | DIDEUTERATED CAMPTOTHECIN DERIVATIVE AND PREPARATION METHOD THEREFOR | 上海禧耀医药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |
| WO-2023220223-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| US-11639353-B2 | Cyclobutanes- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-05-02 | — | — | US | disclosed |
| US-11572398-B2 | GLP-1 derivatives and uses thereof | NOVO NORDISK A/S (DK) | 2023-02-07 | — | — | US | disclosed |
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |
| US-20220169676-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | WASHINGTON UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |
| US-11224224-B2 | Thiobenzoimidazole as fungicides | REDAG CROP PROTECTION LTD. (GB) | 2022-01-18 | — | — | US | disclosed |
| CN-1372465-A | antifungal agents | NOVARTIS AG (CH) | 2002-10-02 | — | — | CN | disclosed |
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| CN-1345313-A | Pesticidal enantiomer-pure 2,4-disubstituted oxazolines | NOVARTIS AG (CH) | 2002-04-17 | — | — | CN | disclosed |
| CN-1326442-A | Pesticides | NOVARTIS AG (CH) | 2001-12-12 | — | — | CN | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |
| CN-1224001-A | Process for preparation of carbonates and polycarbonates | MONSANTO CO (US) | 1999-07-28 | — | — | CN | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5627194-A | FOR TREATING HERPES VIRUS INFECTIONS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-05-06 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11224224-B2 | Thiobenzoimidazole as fungicides | CYP1B1, CYP51A1, CYP1A2 | ATM 4475/4885TOP2A 923/4885TOP2B 342/4885 |
| US-11572398-B2 | GLP-1 derivatives and uses thereof | GLP1R, GIPR, GCG | ATM 4864/4885TOP2A 4685/4885TOP2B 4745/4885 |
| US-20220169676-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | HDGF, MMP7, HGF | ATM 2848/4885TOP2A 2805/4885TOP2B 3355/4885 |
| US-11639353-B2 | Cyclobutanes- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | ITGB1, ITGB2, ITGA1 | ATM 2886/4885TOP2A 2456/4885TOP2B 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.