Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 5/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228087 | 1.00 | ESR1 (0.33) | ESR1ESR2ESRRGOPRM1OPRD1 | |
| SCHEMBL227057 | 0.92 | ESR1 (0.41) | ESR1ESR2ESRRGOPRM1OPRD1 | |
| SCHEMBL227056 | 0.92 | ESR1 (0.41) | ESR1ESR2ESRRGOPRM1OPRD1 | |
| SCHEMBL225691 | 0.90 | ESR1 (0.39) | ESR1ESR2MCHR1KMT2AMEN1 | |
| SCHEMBL225692 | 0.90 | ESR1 (0.39) | ESR1ESR2MCHR1KMT2AMEN1 | |
| SCHEMBL225204 | 0.89 | TUBB4A (0.36) | ESR1ESR2MCHR1ACHECA1 | |
| SCHEMBL226129 | 0.88 | GPR119 (0.41) | KMT2AMEN1 | |
| SCHEMBL227300 | 0.84 | ESR1 (0.35) | ESR1ESR2OPRM1OPRD1MCHR1 | |
| SCHEMBL227299 | 0.84 | ESR1 (0.35) | ESR1ESR2OPRM1OPRD1MCHR1 | |
| SCHEMBL228415 | 0.83 | ESR1 (0.33) | ESR1ESR2MCHR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004315-A1 | Selective Estrogen Receptor Modulator | RADIUS HEALTH, INC. | 2012-01-05 | — | — | US | disclosed |
| US-7960412-B2 | Selective estrogen receptor modulator | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004315-A1 | Selective Estrogen Receptor Modulator | ESR1, GPER1, ESR2 | ESR1 1/4885ESR2 3/4885ESRRG 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.