Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055912 | 0.95 | SLC6A4 (0.51) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL15473214 | 0.80 | SLC6A4 (0.44) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL9888298 | 0.80 | KMT2A (0.46) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL22809555 | 0.79 | SLC6A4 (0.50) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL18071748 | 0.79 | SLC6A4 (0.43) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL7018753 | 0.79 | PPARG (0.45) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL23207581 | 0.77 | MTNR1A (0.51) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL12958117 | 0.77 | SLC6A4 (0.42) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL14533179 | 0.76 | SLC6A4 (0.75) | SLC6A4MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL250835 | 0.76 | SLC6A4 (0.44) | SLC6A4MEN1KMT2ALMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |