Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28350715 | 0.98 | SLC7A5 (0.49) | SLC7A5PDE2AEPHX2PDK2TAAR1 | |
| Hydrochloric Acid SCHEMBL30450035 | 0.98 | SLC7A5 (0.49) | SLC7A5PDE2AEPHX2PDK2TAAR1 | |
| SCHEMBL22809647 | 0.87 | SMN1; SMN2 (0.42) | SLC7A5PDE2APDK2TAAR1LTA4H | |
| SCHEMBL22809649 | 0.81 | PDK2 (0.45) | SLC7A5PDE2AEPHX2PDK2FFAR4 | |
| SCHEMBL28351071 | 0.81 | EPHX2 (0.46) | SLC7A5PDE2AEPHX2FFAR4FFAR1 | |
| SCHEMBL22208515 | 0.79 | SLC7A5 (0.43) | SLC7A5PDE2AEPHX2FFAR4FFAR1 | |
| SCHEMBL31697025 | 0.79 | SLC7A5 (0.43) | SLC7A5PDE2AEPHX2FFAR4FFAR1 | |
| SCHEMBL1290720 | 0.78 | TAAR1 (0.54) | SLC7A5PDK2TAAR1FFAR4LTA4H | |
| Hydrochloric Acid SCHEMBL1623669 | 0.77 | TAAR1 (0.52) | SLC7A5PDK2TAAR1FFAR4LTA4H | |
| SCHEMBL13863767 | 0.77 | EPHX2 (0.49) | SLC7A5PDE2AEPHX2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | RAQUALIA PHARMA INC. (JP) | 2021-10-26 | — | — | US | disclosed |
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | SCN8A, SCN7A, SCN1A | SLC7A5 759/4885PDE2A 497/4885EPHX2 3915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.