Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22809574 | 0.81 | SLC7A5 (0.50) | PDK2KDM4EEPHX2SLC7A5PDE2A | |
| Hydrochloric Acid SCHEMBL28350715 | 0.80 | SLC7A5 (0.49) | PDK2KDM4EEPHX2SLC7A5PDE2A | |
| Hydrochloric Acid SCHEMBL30450035 | 0.80 | SLC7A5 (0.49) | PDK2KDM4EEPHX2SLC7A5PDE2A | |
| SCHEMBL23067893 | 0.79 | HTR1B (0.53) | PDK2HTR1BHTR1DKDM4EALDH1A1 | |
| SCHEMBL30756577 | 0.79 | HTR1B (0.53) | PDK2HTR1BHTR1DKDM4EALDH1A1 | |
| SCHEMBL5535001 | 0.79 | HTR1B (0.58) | PDK2HTR1BHTR1DKDM4EALDH1A1 | |
| SCHEMBL28354491 | 0.79 | PDK2 (0.54) | PDK2EPHX2SCN9A | |
| SCHEMBL18295382 | 0.78 | HTR1B (0.52) | PDK2HTR1BHTR1DKDM4EALDH1A1 | |
| SCHEMBL22809553 | 0.77 | HTR1B (0.56) | PDK2HTR1BHTR1DKDM4EALDH1A1 | |
| SCHEMBL22208515 | 0.77 | SLC7A5 (0.43) | EPHX2SLC7A5PDE2ASCN9AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |