Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832050 | 0.84 | L3MBTL1 (0.60) | MAPTL3MBTL1NPSR1RAB9AKDM4E | |
| SCHEMBL13791556 | 0.82 | L3MBTL1 (0.65) | MAPTL3MBTL1NPSR1RAB9AKDM4E | |
| SCHEMBL24999539 | 0.82 | L3MBTL1 (0.51) | MAPTL3MBTL1NPSR1RAB9AKDM4E | |
| SCHEMBL167016 | 0.82 | L3MBTL1 (0.58) | MAPTL3MBTL1NPSR1RAB9AKDM4E | |
| SCHEMBL29782607 | 0.82 | L3MBTL1 (0.58) | MAPTL3MBTL1NPSR1RAB9AKDM4E | |
| SCHEMBL15832087 | 0.82 | L3MBTL1 (0.50) | MAPTL3MBTL1NPSR1KDM4EPOLB | |
| SCHEMBL28920293 | 0.81 | L3MBTL1 (0.68) | MAPTL3MBTL1NPSR1RAB9AKDM4E | |
| SCHEMBL30010505 | 0.81 | L3MBTL1 (0.68) | MAPTL3MBTL1NPSR1RAB9AKDM4E | |
| SCHEMBL2576322 | 0.81 | MAPT (0.52) | MAPTL3MBTL1NPSR1RAB9ALMNA | |
| SCHEMBL27295380 | 0.81 | MAPT (0.57) | MAPTL3MBTL1NPSR1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239134-B1 | PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2020-12-23 | — | — | EP | disclosed |