Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666892 | 1.00 | BCHE (0.47) | BCHEACHESLC6A2HTR1ATAAR1 | |
| SCHEMBL16774604 | 0.86 | GJB2 (0.41) | BCHEACHESLC6A2SSTR1SSTR2 | |
| SCHEMBL15481846 | 0.86 | GJB2 (0.41) | BCHEACHESLC6A2HTR1ASSTR1 | |
| SCHEMBL20140085 | 0.84 | BCHE (0.55) | BCHEACHESLC6A2HTR1ATAAR1 | |
| SCHEMBL22316285 | 0.84 | BCHE (0.55) | BCHEACHESLC6A2HTR1ATAAR1 | |
| SCHEMBL23225625 | 0.84 | SLC6A2 (0.52) | BCHEACHESLC6A2TSHRPDE4D | |
| SCHEMBL18896702 | 0.84 | BCHE (0.55) | BCHEACHESLC6A2HTR1ATAAR1 | |
| SCHEMBL19380966 | 0.84 | BCHE (0.55) | BCHEACHESLC6A2HTR1ATAAR1 | |
| SCHEMBL13446337 | 0.84 | BCHE (0.55) | BCHEACHESLC6A2HTR1ATAAR1 | |
| SCHEMBL18485164 | 0.84 | BCHE (0.55) | BCHEACHESLC6A2HTR1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184112-B1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE | FUJIFILM CORP (JP) | 2020-12-23 | — | — | EP | disclosed |