Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.41 |
| ▸ | GJA1 | P17302 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810276 | 0.87 | GJB2 (0.43) | GJB2GJA1TACR1NAAAAGXT | |
| SCHEMBL15481846 | 0.86 | GJB2 (0.41) | GJB2GJA1TACR1BCHEACHE | |
| SCHEMBL18666892 | 0.86 | BCHE (0.47) | GJB2BCHEACHESLC6A2SSTR1 | |
| SCHEMBL22810243 | 0.86 | BCHE (0.47) | GJB2BCHEACHESLC6A2SSTR1 | |
| SCHEMBL21754810 | 0.76 | GJB2 (0.43) | GJB2GJA1AGXTKCNH2TACR2 | |
| SCHEMBL15481960 | 0.75 | GJB2 (0.42) | GJB2GJA1KCNH2TACR2SSTR1 | |
| SCHEMBL15481954 | 0.75 | GJA1 (0.45) | GJB2GJA1TACR2 | |
| SCHEMBL16756780 | 0.75 | GJB2 (0.47) | GJB2GJA1TACR2 | |
| SCHEMBL15481973 | 0.74 | GJA1 (0.37) | GJB2GJA1TACR1NAAABCHE | |
| SCHEMBL15481946 | 0.74 | GJB2 (0.46) | GJB2GJA1TACR2SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184112-A1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-SS-D-ARABINOFURANOSYL)CYTOSINE | Fujifilm Corporation (JP) | 2017-06-28 | — | — | EP | disclosed |
| EP-2883866-A1 | INTERMEDIATE FOR SYNTHESIS OF 1-(2-DEOXY-2-FLUORO-4-THIO-beta-D-ARABINOFURANOSYL) CYTOSINE, INTERMEDIATE FOR SYNTHESIS OF THIONUCLEOSIDE, AND METHODS FOR PRODUCING THESE INTERMEDIATES | FUJIFILM Corporation (JP) | 2015-06-17 | — | — | EP | disclosed |