Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208738 | 0.91 | TSHR (0.37) | TSHRHSD17B10MAPK1ACP1ABCG2 | |
| SCHEMBL20209210 | 0.88 | P2RX4 (0.31) | — | |
| SCHEMBL20208801 | 0.87 | HSD17B10 (0.38) | TSHRHSD17B10MAPK1ACP1ABCG2 | |
| SCHEMBL20209195 | 0.86 | ALDH1A1 (0.31) | HSD17B10ALDH1A1USP2CYP1A2CYP3A4 | |
| SCHEMBL22812396 | 0.86 | GLA (0.31) | TSHRHSD17B10ALDH1A1 | |
| SCHEMBL22146057 | 0.85 | CYP1A2 (0.38) | TSHRHSD17B10MAPK1ACP1ABCG2 | |
| SCHEMBL22812377 | 0.84 | KDM4E (0.31) | MEN1KMT2A | |
| SCHEMBL20208799 | 0.82 | ALDH1A1 (0.39) | HSD17B10MAPK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20209209 | 0.81 | MEN1 (0.31) | TSHRMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL22812594 | 0.80 | MAPK1 (0.35) | TSHRMAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |