Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22812430 | 0.91 | TSHR (0.39) | TSHRHSD17B10MAPK1ACP1ABCG2 | |
| SCHEMBL20208740 | 0.83 | ALDH1A1 (0.38) | HSD17B10MAPK1ALDH1A1LMNAHTT | |
| SCHEMBL20208958 | 0.83 | ALDH1A1 (0.38) | HSD17B10MAPK1ALDH1A1LMNAHTT | |
| SCHEMBL22812406 | 0.83 | L3MBTL1 (0.38) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL22146057 | 0.83 | CYP1A2 (0.38) | TSHRHSD17B10MAPK1ACP1ABCG2 | |
| SCHEMBL20209195 | 0.82 | ALDH1A1 (0.31) | HSD17B10USP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20208635 | 0.80 | KDM4E (0.38) | KMT2A | |
| SCHEMBL20209193 | 0.80 | EDNRB (0.33) | ALDH1A1HTT | |
| SCHEMBL22146098 | 0.79 | ACP1 (0.39) | TSHRHSD17B10MAPK1ACP1ABCG2 | |
| SCHEMBL20209210 | 0.79 | P2RX4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544986-B1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| WO-2018095839-A1 | BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |