Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25033288 | 0.86 | HRH3 (0.38) | OPRM1OPRL1CHRM2CHRM4CHRM5 | |
| SCHEMBL25090134 | 0.81 | CHRM2 (0.30) | OPRM1OPRL1CHRM2CHRM4CHRM5 | |
| SCHEMBL824131 | 0.80 | OPRL1 (0.49) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL9976590 | 0.76 | OPRM1 (0.50) | OPRM1OPRL1OPRK1OPRD1CHRM2 | |
| SCHEMBL24585209 | 0.76 | OPRM1 (0.54) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL12423917 | 0.76 | OPRL1 (0.37) | OPRM1OPRL1OPRK1OPRD1CHRM1 | |
| SCHEMBL14098626 | 0.75 | NCF1 (0.37) | OPRM1CHRM2CHRM1 | |
| SCHEMBL12398698 | 0.75 | NCF1 (0.37) | OPRM1CHRM2CHRM1 | |
| SCHEMBL12563449 | 0.75 | NCF1 (0.37) | OPRM1CHRM2CHRM1 | |
| SCHEMBL22874788 | 0.74 | OPRM1 (0.49) | OPRM1OPRL1OPRK1OPRD1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252589-A1 | IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | Precision Nanosystems Inc. (CA) | 2020-12-24 | — | — | WO | disclosed |