Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22815942 | 0.90 | CYP19A1 (0.45) | CYP19A1GABRA2GABRB2SMN1; SMN2HPGD | |
| SCHEMBL22816427 | 0.84 | CYP19A1 (0.42) | CYP19A1SMN1; SMN2HPGDKDM4EMAPT | |
| SCHEMBL22815829 | 0.83 | CYP19A1 (0.45) | CYP19A1SMN1; SMN2HPGDKDM4EPOLB | |
| SCHEMBL22815645 | 0.83 | CYP19A1 (0.48) | CYP19A1GABRA2GABRB2SMN1; SMN2HPGD | |
| SCHEMBL22816960 | 0.83 | POLB (0.40) | CYP19A1SMN1; SMN2HPGDKDM4EMAPT | |
| SCHEMBL22816919 | 0.81 | CYP19A1 (0.46) | CYP19A1GABRA2GABRB2SMN1; SMN2HPGD | |
| SCHEMBL22815917 | 0.80 | CYP19A1 (0.42) | CYP19A1GABRA2GABRB2SMN1; SMN2HPGD | |
| SCHEMBL22816961 | 0.79 | ALOX15 (0.42) | HPGDKDM4EMAPTPOLBMEN1 | |
| SCHEMBL22815696 | 0.79 | CYP19A1 (0.65) | CYP19A1GABRA2GABRB2SMN1; SMN2HPGD | |
| SCHEMBL22815756 | 0.79 | CYP19A1 (0.49) | CYP19A1GABRA2GABRB2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |