Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21296940 | 0.89 | MEN1 (0.54) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22816573 | 0.88 | MEN1 (0.49) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22816473 | 0.87 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22816737 | 0.86 | ALOX15 (0.49) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22815706 | 0.84 | POLB (0.47) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22816820 | 0.84 | MEN1 (0.46) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22815714 | 0.84 | TP53 (0.54) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22815947 | 0.83 | AKR1C3 (0.45) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22816699 | 0.81 | AKR1C3 (0.49) | MEN1KMT2APOLBL3MBTL1ALOX15 | |
| SCHEMBL22815530 | 0.81 | TP53 (0.52) | MEN1KMT2AL3MBTL1ALOX15AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |