Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.71 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16062286 | 0.86 | KDM4E (0.60) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL2754679 | 0.82 | KDM4E (0.53) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL29648218 | 0.82 | CA12 (0.55) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL2754694 | 0.82 | CA12 (0.55) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL16744389 | 0.82 | MTNR1A (0.71) | MTNR1AMTNR1BL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL3264491 | 0.82 | MTNR1A (0.71) | MTNR1AMTNR1BL3MBTL1ALDH1A1LMNA | |
| SCHEMBL4544125 | 0.82 | KDM4E (0.62) | L3MBTL1KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL17029228 | 0.81 | KDM4E (0.55) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL15300802 | 0.81 | MTNR1A (0.73) | MTNR1AMTNR1BL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL885015 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |