Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.71 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483070 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BMAPT | |
| SCHEMBL2187414 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL16744389 | 0.82 | MTNR1A (0.71) | MTNR1AMTNR1BL3MBTL1USP2ALOX15 | |
| SCHEMBL22816591 | 0.82 | MTNR1A (0.71) | MTNR1AMTNR1BL3MBTL1MAPTUSP2 | |
| SCHEMBL5113209 | 0.81 | MTNR1A (0.73) | MTNR1AMTNR1BL3MBTL1MAPTUSP2 | |
| SCHEMBL885015 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BL3MBTL1USP2ALOX15 | |
| SCHEMBL528393 | 0.79 | MTNR1A (0.68) | MTNR1AMTNR1BL3MBTL1USP2ALOX15 | |
| SCHEMBL30756752 | 0.79 | HTR1B (0.61) | LMNAALDH1A1PDK2 | |
| SCHEMBL13272286 | 0.79 | HTR1B (0.61) | LMNAALDH1A1PDK2 | |
| SCHEMBL23067913 | 0.79 | DRD2 (0.55) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138707-A9 | QUINUCLIDINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2010-01-28 | — | — | WO | disclosed |