Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | LPL | P06858 | 10/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 10/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28988087 | 0.79 | NOTUM (0.43) | BACE1LPLLIPGROCK1IRAK4 | |
| SCHEMBL23484481 | 0.77 | BACE1 (0.38) | BACE1LPLLIPGROCK1IRAK4 | |
| SCHEMBL15096664 | 0.75 | LIPG (0.42) | BACE1LPLLIPGROCK1IRAK4 | |
| SCHEMBL15854890 | 0.74 | LIPG (0.41) | LPLLIPGROCK1IRAK4EGFR | |
| SCHEMBL23564363 | 0.71 | ROCK1 (0.37) | BACE1LPLLIPGROCK1IRAK4 | |
| SCHEMBL24741504 | 0.70 | LPL (0.38) | BACE1LPLLIPGROCK1IRAK4 | |
| SCHEMBL4758599 | 0.70 | LPL (0.38) | BACE1LPLLIPGROCK1IRAK4 | |
| SCHEMBL22816709 | 0.69 | BACE1 (0.40) | BACE1LPLLIPGROCK1IRAK4 | |
| SCHEMBL22655375 | 0.69 | BACE1 (0.44) | BACE1LPLLIPGROCK1IDO1 | |
| SCHEMBL15795865 | 0.69 | PRF1 (0.41) | BACE1LPLLIPGROCK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |