Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14212260 | 0.84 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL29634547 | 0.84 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL15335321 | 0.78 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL30544472 | 0.75 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL3148663 | 0.75 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16382823 | 0.70 | CA1 (0.40) | LPLLIPGPTGS1PTGS2CA1 | |
| SCHEMBL29775936 | 0.68 | PRKCI (0.41) | LPLLIPGF11 | |
| SCHEMBL4427556 | 0.68 | PRKCI (0.41) | LPLLIPGF11 | |
| SCHEMBL1803570 | 0.68 | LPL (0.41) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL20527113 | 0.67 | MAOB (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |