Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148663 | 1.00 | LPL (0.44) | LPLLIPGCYP3A4ATMPOLB | |
| SCHEMBL29634547 | 0.89 | LPL (0.44) | LPLLIPGPOLBCA1CA2 | |
| SCHEMBL14212260 | 0.89 | LPL (0.44) | LPLLIPGPOLBCA1CA2 | |
| SCHEMBL15335321 | 0.86 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL5899518 | 0.86 | POLB (0.40) | CYP3A4ATMPOLBALDH1A1HSD17B10 | |
| SCHEMBL14746387 | 0.83 | ALDH1A1 (0.55) | LPLLIPGPOLBCA1CA2 | |
| SCHEMBL10074115 | 0.79 | LPL (0.48) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL10074112 | 0.79 | LPL (0.48) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL21731053 | 0.79 | CYP3A4 (0.39) | CYP3A4ATMPOLBALDH1A1HSD17B10 | |
| SCHEMBL5899619 | 0.79 | CYP3A4 (0.39) | CYP3A4ATMPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908944-A | Crystal of sulfamide pyrimidine derivative and application thereof | 正大天晴药业集团股份有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118480033-A | Crystal form of pyrimidine sulfonamide compound and preparation method thereof | 无锡智康弘义生物科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118201924-A | Heterocyclic compounds and their use | 万特斯治疗美国公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118201908-A | Azabiphenyls and uses thereof | 正大天晴药业集团股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116724042-A | Heterotricyclic compound and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-09-08 | — | — | CN | disclosed |