SCHEMBL22817

SCHEMBL22817

COc1cc(N)ccc1Nc1cc(Nc2ccc(N)cc2OC)cc(Nc2ccc(N)cc2OC)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.56
ALDH1A1 P00352 6/20 0.56
MAPK1 P28482 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
GAA P10253 6/20 0.48
HTT P42858 2/20 0.48
TSHR P16473 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 4/20 0.44
NR4A1 P22736 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
ALOX15 P16050 1/20 0.42
USP2 O75604 1/20 0.42
TNIK Q9UKE5 1/20 0.42
LMNA P02545 1/20 0.41
DHFR P00374 1/20 0.38
IMPDH2 P12268 1/20 0.38
IMPDH1 P20839 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29763992 1.00 MAPT (0.56) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL2127164 0.87 ALDH1A1 (0.65) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL7105484 0.80 MAPT (0.57) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL14453287 0.76 MAPT (0.52) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL29544483 0.76 MAPT (0.47) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL29595 0.74 ALDH1A1 (0.50) MAPTALDH1A1L3MBTL1GAAHTT
SCHEMBL29764005 0.74 ALDH1A1 (0.50) MAPTALDH1A1L3MBTL1GAAHTT
SCHEMBL11392957 0.73 MAPT (0.40) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL31539196 0.73 ALDH1A1 (0.59) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL8024114 0.73 MAPT (0.65) MAPTALDH1A1MAPK1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11705555-B2 Electrolyte materials for use in electrochemical cells SION POWER CORPORATION (US) 2023-07-18 US disclosed
US-20230027931-A1 THERMOPLASTIC MOULDING COMPOSITION CONTAINING POLYALKYLENE TEREPHTHALATE BASF SE (DE) 2023-01-26 US disclosed
US-8987357-B2 Thermoplastic molding composition BASF SE (DE) 2015-03-24 US disclosed
US-20140045070-A1 ELECTROCHEMICAL CELLS COMPRISING POLYIMIDES BASF SE (DE) 2014-02-13 US disclosed
EP-2609646-A1 ELECTROLYTE MATERIALS FOR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2013-07-03 EP disclosed
US-20120302677-A1 THERMOPLASTIC MOLDING COMPOSITION BASF SE (DE) 2012-11-29 US disclosed
WO-2012025543-A1 ELECTROLYTE MATERIALS FOR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2012-03-01 WO disclosed
US-8093349-B2 Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same UBE INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-20100009206-A1 TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, METAL-PLATED TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-01-14 US disclosed