Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344842 | 0.83 | MAPT (0.52) | MAPTGAAMAPK1TSHRHTT | |
| Hydrochloric Acid SCHEMBL9513322 | 0.82 | MAPT (0.50) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL22817 | 0.80 | MAPT (0.56) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL29763992 | 0.80 | MAPT (0.56) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL29544483 | 0.79 | MAPT (0.47) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL14453287 | 0.79 | MAPT (0.52) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL16404492 | 0.78 | HPGD (0.55) | MAPTTSHRHTTAPPALDH1A1 | |
| SCHEMBL25091235 | 0.78 | MAPT (0.51) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL6572605 | 0.77 | APP (0.43) | MAPTGAAMAPK1TSHRHTT | |
| SCHEMBL6572330 | 0.77 | HTR7 (0.45) | MAPTGAAMAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146350-A2 | Hair treatment composition | UNILEVER PLC (GB) | 1985-06-26 | — | — | EP | claimed |
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |
| WO-2020203818-A1 | ASBESTOS DETECTING AGENT, ASBESTOS DETECTING KIT, AND ASBESTOS DETECTING METHOD | 広島県 | 2020-10-08 | — | — | WO | disclosed |
| CN-102811998-B | Novel cyclophilin inhibitors and uses thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-03-30 | — | — | CN | disclosed |
| US-9174940-B2 | TSH receptor antagonizing tetrahydroquinoline compounds | MERCK SHARP & DOHME B.V. (NL) | 2015-11-03 | — | — | US | disclosed |
| CN-102811998-A | Novel cyclophilin inhibitors and uses thereof | INST NAT SANTE RECH MED | 2012-12-05 | — | — | CN | disclosed |
| US-20110172267-A1 | TSH receptor antagonizing tetrahydroquinoline compounds | N.V. ORGANON | 2011-07-14 | — | — | US | disclosed |
| EP-1341502-A2 | HAIR CONDITIONING COMPOSITIONS AND THEIR USE IN HAIR COLOURING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002047632-A2 | HAIR CONDITIONING COMPOSITIONS COMPRISING AMINOFUNCTIONA POLYSILOXANES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-4268264-A | ORTHO PRECURSORS SELECTED FROM AROMATIC DIAMINES, AMINOPHENOL, DIPHENOL, AND PHENYLENEDIAMINE | L'OREAL (FR) | 1981-05-19 | — | — | US | disclosed |
| US-4213914-A | ADDITION-CONDENSATION COPOLYMERS | RHONE-POULENC INDUSTRIES (FR) | 1980-07-22 | — | — | US | disclosed |
| US-4196145-A | OXIDATION COLOR DYES | CLAIROL INCORPORATED (US) | 1980-04-01 | — | — | US | disclosed |
| US-4147711-A | Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom | RHONE-POULENC INDUSTRIES (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4092102-A | HAIR DYES, OXIDATION DYES | CLAIROL INCORPORATED (US) | 1978-05-30 | — | — | US | disclosed |
| US-4088670-A | P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID | RHONE-POULENC INDUSTRIES (FR) | 1978-05-09 | — | — | US | disclosed |
| US-4057518-A | Process for the manufacture of heat resistant multicellular materials | RHONE-POULENC INDUSTRIES (FR) | 1977-11-08 | — | — | US | disclosed |
| US-4013600-A | STORAGE STABILITY | RHONE-POULENC INDUSTRIES (FR) | 1977-03-22 | — | — | US | disclosed |
| US-4010220-A | AMINO COMPOUND, POLYURETHANE ELASTOMER | RHONE-POULENC INDUSTRIES (FR) | 1977-03-01 | — | — | US | disclosed |
| US-3970423-A | PHENYLENEDIAMINE DERIVATIVES | CLAIROL INCORPORATED (US) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172267-A1 | TSH receptor antagonizing tetrahydroquinoline compounds | TSHR, MC1R, TRHR | MAPT 4770/4885GAA 2913/4885MAPK1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.