Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24499895 | 0.83 | PI4KA (0.61) | MAPK1ALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL8175179 | 0.83 | PI4KA (0.61) | MAPK1ALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12832016 | 0.83 | PI4KA (0.61) | MAPK1ALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20794210 | 0.83 | PI4KA (0.61) | MAPK1ALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7151977 | 0.83 | PI4KA (0.61) | MAPK1ALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL14276903 | 0.82 | LMNA (0.48) | ALDH1A1TP53PDE4DYTHDC1ADORA2A | |
| SCHEMBL24600957 | 0.80 | ALDH1A1 (0.60) | MAPK1ALDH1A1CYP1A2HIF1AADA | |
| SCHEMBL2035453 | 0.80 | ALDH1A1 (0.60) | MAPK1ALDH1A1CYP1A2HIF1AADA | |
| SCHEMBL2035452 | 0.80 | ALDH1A1 (0.60) | MAPK1ALDH1A1CYP1A2HIF1AADA | |
| SCHEMBL27574575 | 0.80 | BCHE (0.44) | CYP2C19MAPK1ALDH1A1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253870-A1 | 6-HYDRAZINOADENOSINE COMPOUND HAVING A2A ADENOSINE RECEPTOR AGONIST ACTIVITY | 中国人民解放军军事科学院军事医学研究院 | 2020-12-24 | — | — | WO | disclosed |