Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10094675 | 0.90 | MEN1 (0.50) | PTGS2S1PR1CTSAABL1MAPT | |
| SCHEMBL10305002 | 0.88 | PTGS2 (0.49) | PTGS2PTGS1S1PR1CTSAABL1 | |
| SCHEMBL10304909 | 0.82 | S1PR1 (0.46) | S1PR1ERN1 | |
| SCHEMBL14499414 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1PDGFRBPDGFRAMAPT | |
| SCHEMBL256798 | 0.81 | MAPT (0.50) | PTGS2PTGS1PDGFRBPDGFRAMAPT | |
| SCHEMBL22820004 | 0.78 | ABL1 (0.50) | PTGS2PTGS1ABL1 | |
| SCHEMBL3750244 | 0.77 | ABL1 (0.51) | PTGS2ABL1 | |
| SCHEMBL16945922 | 0.77 | PTGS2 (0.52) | PTGS2PTGS1S1PR1PDGFRBPDGFRA | |
| SCHEMBL12326161 | 0.77 | PDGFRB (0.58) | PTGS2PTGS1PDGFRBPDGFRAMAPT | |
| SCHEMBL10304910 | 0.77 | HTR7 (0.44) | S1PR1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255425-A1 | ANTI-HBV AGENT | 国立研究開発法人理化学研究所 | 2020-12-24 | — | — | WO | disclosed |