Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25006066 | 0.89 | JAK2 (0.61) | JAK2MEN1KMT2APAX8STING1 | |
| SCHEMBL25005417 | 0.86 | JAK2 (0.67) | JAK2MEN1KMT2APAX8STING1 | |
| SCHEMBL25005574 | 0.81 | JAK2 (0.64) | JAK2MEN1KMT2APAX8STING1 | |
| SCHEMBL24291456 | 0.81 | LMNA (0.71) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL22822605 | 0.80 | JAK2 (0.72) | JAK2MEN1KMT2APAX8STING1 | |
| SCHEMBL29462179 | 0.80 | JAK2 (0.72) | JAK2MEN1KMT2APAX8STING1 | |
| SCHEMBL22804228 | 0.80 | JAK2 (0.75) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL22804227 | 0.78 | JAK2 (0.69) | JAK2MEN1KMT2APAX8STING1 | |
| SCHEMBL24291403 | 0.78 | JAK2 (0.68) | JAK2MEN1KMT2APAX8STING1 | |
| SCHEMBL25005925 | 0.77 | EPHX2 (0.63) | JAK2MEN1KMT2APAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253802-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | 北京大学 | 2020-12-24 | — | — | WO | disclosed |