Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24291375 | 0.95 | EPHX2 (0.56) | EPHX2RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL25005417 | 0.80 | JAK2 (0.67) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL25006066 | 0.80 | JAK2 (0.61) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL24291456 | 0.79 | LMNA (0.71) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL28024114 | 0.79 | POLB (0.73) | EPHX2KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6427938 | 0.78 | RAB9A (0.78) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL25005574 | 0.77 | JAK2 (0.64) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL22822784 | 0.77 | JAK2 (0.58) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL22822605 | 0.77 | JAK2 (0.72) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL12514132 | 0.77 | EPHX2 (0.73) | EPHX2ALDH1A1SMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112107568-B | Diaryl amide compound and application thereof | 北京龙嘉博创医药科技有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-112107568-A | Diaryl amide compound and application thereof | 北京大学 | 2020-12-22 | — | — | CN | claimed |
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| CN-112107568-B | Diaryl amide compound and application thereof | 北京龙嘉博创医药科技有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-112107568-A | Diaryl amide compound and application thereof | 北京大学 | 2020-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SLC14A1, SLC28A1, SLC28A2 | EPHX2 3260/4885RAB9A 779/4885NPC1 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.