SCHEMBL22823181

SCHEMBL22823181

CC1(C)c2ccccc2C2(c3ccccc31)c1cc(-c3cccc(N(c4ccccc4)c4ccccc4)c3)sc1C1(c3ccccc3C(C)(C)c3ccccc31)c1cc(-c3cccc(N(c4ccccc4)c4ccccc4)c3)sc12

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ BACE1 P56817 1/20 0.31
▸ BACE2 Q9Y5Z0 1/20 0.31
▸ HSD17B1 P14061 1/20 0.30
▸ HSD17B2 P37059 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22823220 1.00 APP (0.32) APPMEN1NPC1MAPTRAB9A
SCHEMBL22822899 0.93 APP (0.38) APPMEN1MAPTKMT2A
SCHEMBL22823182 0.92 APP (0.39) APPMEN1MAPTKMT2A
SCHEMBL22823622 0.88 APP (0.33) APPHSD17B1HSD17B2
SCHEMBL22823502 0.88 APP (0.33) APPHSD17B1HSD17B2
SCHEMBL22823269 0.86 APP (0.32) APPMEN1NPC1MAPTRAB9A
SCHEMBL22823655 0.85 — —
SCHEMBL22823014 0.85 — —
SCHEMBL22823370 0.85 APP (0.31) APP
SCHEMBL22823186 0.83 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 — — US disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 — — US disclosed
US-20200403161-A1 COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME, DISPLAY PANEL AND DISPLAY DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200403161-A1 COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME, DISPLAY PANEL AND DISPLAY DEVICE TRMT1L, TLK1, TSPO APP 952/4885MEN1 4374/4885NPC1 1711/4885
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device TRMT1L, TLK1, TSPO APP 952/4885MEN1 4374/4885NPC1 1711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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