Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 3/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | SNCA | P37840 | 2/20 | 0.56 |
| ▸ | USP18 | Q9UMW8 | 1/20 | 0.54 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19629172 | 0.85 | ACHE (0.74) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL3005164 | 0.83 | MAPT (0.50) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL3005167 | 0.83 | MAPT (0.50) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL16755530 | 0.82 | ALDH1A1 (0.71) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL16769899 | 0.82 | ALDH1A1 (0.71) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL16755532 | 0.82 | ALDH1A1 (0.71) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL15562912 | 0.81 | ALDH1A1 (0.70) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL16755540 | 0.81 | ACHE (0.78) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL16755537 | 0.81 | ACHE (0.78) | MAPTALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL16769890 | 0.81 | ALDH1A1 (0.70) | MAPTALDH1A1LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399220-A1 | 3,5-DIARYLIDENYL-N-SUBSTITUTED-PIPERID-4-ONE-DERIVED INHIBITORS OF STAT3 PATHWAY ACTIVITY AND USES THEREOF | KIAKOS KONSTANTINOS (AT) | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399220-A1 | 3,5-DIARYLIDENYL-N-SUBSTITUTED-PIPERID-4-ONE-DERIVED INHIBITORS OF STAT3 PATHWAY ACTIVITY AND USES THEREOF | STAT3, JAK2, STAT6 | MAPT 4414/4885ALDH1A1 928/4885LMNA 3396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.