Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602013 | 1.00 | MAPT (0.35) | MAPTNOTUMAAK1POLBSMN1; SMN2 | |
| SCHEMBL28673194 | 0.88 | PPARA (0.36) | MAPTNOTUMAAK1FPR2 | |
| SCHEMBL28673193 | 0.88 | PPARA (0.36) | MAPTNOTUMAAK1FPR2 | |
| SCHEMBL29601859 | 0.85 | TAS1R3 (0.34) | MAPTAAK1 | |
| SCHEMBL28463373 | 0.83 | MAPT (0.38) | MAPTNOTUMPOLBSMN1; SMN2F9 | |
| SCHEMBL28457438 | 0.83 | MAPT (0.38) | MAPTNOTUMPOLBSMN1; SMN2F9 | |
| SCHEMBL28457435 | 0.83 | MAPT (0.38) | MAPTNOTUMPOLBSMN1; SMN2F9 | |
| SCHEMBL22805703 | 0.79 | LMNA (0.44) | MAPTAAK1POLBSMN1; SMN2F9 | |
| SCHEMBL22805702 | 0.79 | LMNA (0.44) | MAPTAAK1POLBSMN1; SMN2F9 | |
| SCHEMBL22823913 | 0.78 | AAK1 (0.37) | MAPTNOTUMAAK1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254559-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2020-12-24 | — | — | WO | disclosed |