SCHEMBL22823920

SCHEMBL22823920

CCC(F)(F)c1cc(F)c(Cl)cc1O[C@@H](C)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPOX P50336 2/20 0.39
F9 P00740 1/20 0.36
PLAU P00749 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
KDM4E B2RXH2 2/20 0.35
GAA P10253 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HPGD P15428 2/20 0.33
MAPK1 P28482 1/20 0.33
LMNA P02545 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.32
RORC P51449 1/20 0.32
TSHR P16473 2/20 0.32
DHODH Q02127 2/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601786 0.90 F9 (0.39) PPOXF9PLAUSMN1; SMN2KDM4E
SCHEMBL22823852 0.90 F9 (0.39) PPOXF9PLAUSMN1; SMN2KDM4E
SCHEMBL28677988 0.88 PTGDR2 (0.42) PPOXSMN1; SMN2KDM4EALDH1A1KMT2A
SCHEMBL29365346 0.88 PTGDR2 (0.42) PPOXSMN1; SMN2KDM4EALDH1A1KMT2A
SCHEMBL28677987 0.88 PTGDR2 (0.42) PPOXSMN1; SMN2KDM4EALDH1A1KMT2A
SCHEMBL29601955 0.85 PPOX (0.34) PPOXSMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL22823913 0.83 AAK1 (0.37) PPOXF9PLAUSMN1; SMN2KDM4E
SCHEMBL29602064 0.83 AAK1 (0.37) PPOXF9PLAUSMN1; SMN2KDM4E
SCHEMBL28672447 0.82 PTGDR2 (0.42) PPOXSMN1; SMN2KDM4EALDH1A1KMT2A
SCHEMBL28672449 0.82 PTGDR2 (0.42) PPOXSMN1; SMN2KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415771-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2025-09-16 US disclosed
EP-3986852-B1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-10-16 EP disclosed
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2022-12-08 US disclosed
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2022-12-08 US disclosed
EP-3986852-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2022-04-27 EP disclosed
WO-2020254559-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2020-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS RYR1, CACNB1, SMN1; SMN2 PPOX 3561/4885F9 4558/4885PLAU 4540/4885
US-12415771-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, SMN1; SMN2 PPOX 3561/4885F9 4558/4885PLAU 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.