SCHEMBL29601786

SCHEMBL29601786

CCC(F)(F)c1cc(F)c(F)cc1O[C@@H](C)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F9 P00740 1/20 0.39
PLAU P00749 1/20 0.39
SMN1; SMN2 Q16637 5/20 0.34
POLB P06746 2/20 0.34
ALDH1A1 P00352 4/20 0.33
GAA P10253 3/20 0.33
KDM4E B2RXH2 2/20 0.33
TSHR P16473 3/20 0.33
HPGD P15428 3/20 0.33
NPSR1 Q6W5P4 3/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPK1 P28482 2/20 0.33
PPOX P50336 1/20 0.32
ALDH2 P05091 1/20 0.32
LMNA P02545 3/20 0.32
TP53 P04637 2/20 0.31
RXFP1 Q9HBX9 1/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22823852 1.00 F9 (0.39) F9PLAUSMN1; SMN2POLBALDH1A1
SCHEMBL22823913 0.90 AAK1 (0.37) F9PLAUSMN1; SMN2POLBALDH1A1
SCHEMBL22823920 0.90 PPOX (0.39) F9PLAUSMN1; SMN2POLBALDH1A1
SCHEMBL29602064 0.90 AAK1 (0.37) F9PLAUSMN1; SMN2POLBALDH1A1
SCHEMBL24775126 0.87 F9 (0.34) F9PLAUSMN1; SMN2POLB
SCHEMBL29602001 0.87 F9 (0.34) F9PLAUSMN1; SMN2POLB
SCHEMBL22804299 0.86 KMT2A (0.39) POLBALDH1A1KDM4ETSHRHPGD
SCHEMBL22804300 0.86 KMT2A (0.39) POLBALDH1A1KDM4ETSHRHPGD
SCHEMBL24775125 0.82 SMN1; SMN2 (0.37) F9PLAUSMN1; SMN2POLBALDH1A1
SCHEMBL29601813 0.82 SMN1; SMN2 (0.37) F9PLAUSMN1; SMN2POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415771-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2025-09-16 US disclosed
EP-3986852-B1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-10-16 EP disclosed
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2022-12-08 US disclosed
EP-3986852-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS RYR1, CACNB1, SMN1; SMN2 F9 4558/4885PLAU 4540/4885SMN1; SMN2 3/4885
US-12415771-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, SMN1; SMN2 F9 4558/4885PLAU 4540/4885SMN1; SMN2 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.