Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669001 | 0.87 | ALDH1A1 (0.48) | ALDH1A1BCHEHIF1ACTSAACHE | |
| SCHEMBL25915989 | 0.85 | ALDH1A1 (0.57) | ALDH1A1BCHEHIF1AL3MBTL1CA12 | |
| SCHEMBL22824203 | 0.79 | ALDH1A1 (0.41) | ALDH1A1BCHEHIF1AMMP1MMP2 | |
| SCHEMBL24540277 | 0.73 | CTSA (0.36) | ALDH1A1BCHEHIF1ACTSAACHE | |
| SCHEMBL22995592 | 0.73 | CTSA (0.36) | ALDH1A1BCHEHIF1ACTSAACHE | |
| SCHEMBL26522315 | 0.71 | CTSA (0.34) | ALDH1A1CTSAACHEKDM4E | |
| SCHEMBL18481884 | 0.71 | ALDH1A1 (0.68) | ALDH1A1BCHEHIF1ACA12CA1 | |
| SCHEMBL20078943 | 0.68 | KDM4E (0.44) | ALDH1A1BCHEHIF1ACTSAACHE | |
| SCHEMBL24540480 | 0.67 | — | — | |
| SCHEMBL28660598 | 0.67 | CTSA (0.43) | ALDH1A1BCHEHIF1ACTSAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022126275-A1 | RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-23 | — | — | WO | disclosed |
| WO-2020252598-A1 | RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2020-12-24 | — | — | WO | disclosed |