SCHEMBL24540277

SCHEMBL24540277

CCNP(=O)(OC)OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.36
ACHE P22303 1/20 0.36
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
BCHE P06276 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19525797 0.81
SCHEMBL22823955 0.73 ALDH1A1 (0.48) CTSAACHEKDM4EALDH1A1BCHE
SCHEMBL23979197 0.71 KDM4E (0.42) CTSAACHEKDM4EALDH1A1POLB
SCHEMBL25894071 0.71 CTSA (0.33) CTSAACHEKDM4E
SCHEMBL22995592 0.70 CTSA (0.36) CTSAACHEKDM4EALDH1A1BCHE
SCHEMBL26522315 0.68 CTSA (0.34) CTSAACHEKDM4EALDH1A1
SCHEMBL18787614 0.68 MMP2 (0.35) CTSAACHE
SCHEMBL17915527 0.68 TSHR (0.32)
SCHEMBL23354583 0.67 CTSA (0.37) CTSAACHEKDM4EALDH1A1POLB
SCHEMBL3141515 0.66 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022126275-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-06-23 WO disclosed