Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3SLC6A2
The experimentally established mechanism targets of Racephedrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.96 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.96 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.54 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | HBB | P68871 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.96 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.96 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.96 |
| ▸ | RGS12 | O14924 | 1/20 | 0.96 |
| ▸ | GLA | P06280 | 1/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.96 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.96 |
| ▸ | PKM | P14618 | 1/20 | 0.96 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.96 |
| ▸ | TSHR | P16473 | 1/20 | 0.96 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.96 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.96 |
| ▸ | HTR2A | P28223 | 1/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pseudoephedrine SCHEMBL33285 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL321655 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Ephedrine SCHEMBL22822 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Pseudoephedrine SCHEMBL118099 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL28253267 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL22823 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL27878452 | 0.98 | KMT2A (0.96) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL9413942 | 0.98 | KMT2A (0.96) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Pseudoephedrine SCHEMBL17004001 | 0.98 | KMT2A (0.96) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL8098202 | 0.98 | CYP2D6 (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4340 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084804-A | Method for detecting contents of multi-index components of cough syrup oral liquid | — | 2026-05-26 | — | — | CN | claimed |
| CN-122005475-A | Preparation method of apricot Dan Ganwan and fingerprint spectrum method thereof | 河北锦坤动物药业有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-121577804-A | Fingerprint spectrum of Huanglong cough-relieving granule and construction method | 陕西东科制药有限责任公司 | 2026-02-27 | — | — | CN | claimed |
| CN-119970964-A | A Chinese medicinal composition for treating common cold or influenza, and its preparation method | 天士力医药集团股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119868283-A | Granule for treating cough and asthma of children, preparation method and application thereof | 通化万通药业股份有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119780256-A | Method for detecting various main components in Baima oral liquid and application thereof | 济南百鸣生物制药有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119335087-B | Determination method of UPLC fingerprint of children heat-clearing and cough-relieving particles | 珠海天大中医药研究开发有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119335087-A | Determination method of UPLC fingerprint of children heat-clearing and cough-relieving particles | 珠海天大中医药研究开发有限公司 | 2025-01-21 | — | — | CN | claimed |
| EP-4187242-B1 | QUALITY CONTROL METHOD OF DAMPNESS-RESOLVING AND TOXIN-VANQUISHING COMPOSITION | Guangdong yifang pharmaceutical co ltd (CN) | 2025-01-01 | — | — | EP | claimed |
| CN-118584018-B | Characteristic spectrum of children lung-heat clearing and phlegm resolving oral liquid, construction method thereof and multi-index component detection method | 葵花药业集团(冀州)有限公司 | 2024-12-06 | — | — | CN | claimed |
| US-5188826-A | Used for dry eye application, consists of crosslinked acrylic acid polymer, one or more demulcents and vasoconstrictors; administered to eye in drop or gel form and releases water | INSITE VISION INCORPORATED (US) | 1993-02-23 | — | — | US | claimed |
| WO-1992000707-A1 | TOPICAL OPHTHALMIC SUSPENSIONS | INSITE VISION INCORPORATED (US) | 1992-01-23 | — | — | WO | claimed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | claimed |
| US-4734222-A | Composition and method for cleaning soft and hard contact lenses | CIBA-GEIGY CORPORATION (US) | 1988-03-29 | — | — | US | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| US-4603131-A | Method and composition for treating and preventing irritation of the mucous membranes of the nose | BERNSTEIN, JOEL E. | 1986-07-29 | — | — | US | claimed |
| EP-0093373-A1 | Method and composition for treating and preventing irritation of the mucous membranes of the nose | Bernstein, Joel E. (US) | 1983-11-09 | — | — | EP | claimed |
| US-4260596-A | Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same | BRISTOL-MYERS COMPANY (US) | 1981-04-07 | — | — | US | claimed |
| US-RE29875-E | THEOPHYLLINE SOLUBILIZED BY GLYCERYL GUAIACOLATE, POTASSIUM GUAIACOL SULFONATE OR GUAIACOL | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | claimed |
| US-3968245-A | Sympathomimetic topical and percutaneous administration with halogenated promoters | ALZA CORPORATION (US) | 1976-07-06 | — | — | US | claimed |