Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pseudoephedrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | HBB | P68871 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.96 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.96 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.96 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.96 |
| ▸ | RGS12 | O14924 | 1/20 | 0.96 |
| ▸ | GLA | P06280 | 1/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.96 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.96 |
| ▸ | PKM | P14618 | 1/20 | 0.96 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.96 |
| ▸ | TSHR | P16473 | 1/20 | 0.96 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.96 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.96 |
| ▸ | HTR2A | P28223 | 1/20 | 0.96 |
| ▸ | THPO | P40225 | 1/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racephedrine SCHEMBL321655 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Ephedrine SCHEMBL22822 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Pseudoephedrine SCHEMBL118099 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL28253267 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL22824 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL22823 | 1.00 | KMT2A (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL27878452 | 0.98 | KMT2A (0.96) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL9413942 | 0.98 | KMT2A (0.96) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Pseudoephedrine SCHEMBL17004001 | 0.98 | KMT2A (0.96) | KMT2AMEN1HBBADRA2CCYP2D6 | |
| Racephedrine SCHEMBL8098202 | 0.98 | CYP2D6 (1.00) | KMT2AMEN1HBBADRA2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7822 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084804-A | Method for detecting contents of multi-index components of cough syrup oral liquid | — | 2026-05-26 | — | — | CN | claimed |
| CN-122005475-A | Preparation method of apricot Dan Ganwan and fingerprint spectrum method thereof | 河北锦坤动物药业有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-3723692-B1 | MEDICAL WALKER | ENLIGHTEN MOBILITY LLC (US) | 2026-03-11 | — | — | EP | claimed |
| CN-121577804-A | Fingerprint spectrum of Huanglong cough-relieving granule and construction method | 陕西东科制药有限责任公司 | 2026-02-27 | — | — | CN | claimed |
| US-20260028675-A1 | PRECISION MEDICINE FOR PAIN: DIAGNOSTIC BIOMARKERS, PHARMACOGENOMICS, AND REPURPOSED DRUGS | UNIV INDIANA RES & TECH CORP (US) | 2026-01-29 | — | — | US | claimed |
| WO-2025233431-A1 | HETEROMERIC PROTEINS COMPRISING THREE HETEROMERIZATION IMPROVING SUBSTITUTION, PRODUCTION, COMBINATIONS AND APPLICATIONS THEREOF | IMMATICS BIOTECHNOLOGIES GMBH (DE) | 2025-11-13 | — | — | WO | claimed |
| US-12433839-B2 | Sustained release particle formulations | ADARE PHARMACEUTICALS USA, INC. (US) | 2025-10-07 | — | — | US | claimed |
| US-20250248940-A1 | Biopolymer Formulations for Drug Delivery | 11584022 CANADA INC. (CA) | 2025-08-07 | — | — | US | claimed |
| CN-119970964-A | A Chinese medicinal composition for treating common cold or influenza, and its preparation method | 天士力医药集团股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| EP-4547280-A1 | BIOPOLYMER FORMULATIONS FOR DRUG DELIVERY | 11584022 Canada Inc. (CA) | 2025-05-07 | — | — | EP | claimed |
| EP-0279976-A1 | Pseudoephedrine dosage form | ALZA CORPORATION (US) | 1988-08-31 | — | — | EP | claimed |
| US-4758424-A | Medicament adsorbates of decongestants with complex magnesium aluminum silicate and their preparation | WARNER-LAMBERT COMPANY (US) | 1988-07-19 | — | — | US | claimed |
| EP-0241615-A1 | A pharmaceutical composition of phenindamine having enhanced release characteristics | WARNER-LAMBERT COMPANY (US) | 1987-10-21 | — | — | EP | claimed |
| EP-0237159-A2 | 2 Stage drug delivery device | ALZA CORPORATION (US) | 1987-09-16 | — | — | EP | claimed |
| US-4662880-A | Pseudoephedrine, brompheniramine therapy | ALZA CORPORATION (US) | 1987-05-05 | — | — | US | claimed |
| EP-0219458-A2 | Medicament adsorbates and their preparation | WARNER-LAMBERT COMPANY (US) | 1987-04-22 | — | — | EP | claimed |
| EP-0111144-B1 | SUSTAINED RELEASE SOLID DOSAGE FORMS HAVING NON-UNIFORM DISTRIBUTION OF ACTIVE INGREDIENT | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-12-03 | — | — | EP | claimed |
| US-4576645-A | Whipped gel composition | BLOCK DRUG CO., INC. (US) | 1986-03-18 | — | — | US | claimed |
| EP-0111144-A1 | Sustained release solid dosage forms having non-uniform distribution of active ingredient | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-06-20 | — | — | EP | claimed |
| US-4181719-A | Analgesic N-acetyl-para-aminophenyl N'-acetylaminothioalkanoates | STERLING DRUG INC. (US) | 1980-01-01 | — | — | US | claimed |