Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962916 | 0.78 | CA1 (0.56) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL9620273 | 0.76 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL9620563 | 0.76 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22827855 | 0.73 | ALDH1A1 (0.38) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1070351 | 0.73 | CA12 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22827686 | 0.72 | BDKRB1 (0.36) | CA1CA2CA9CA12CA7 | |
| SCHEMBL31381764 | 0.71 | KAT6A (0.40) | CA1CA2KMT2AKAT6A | |
| SCHEMBL9620596 | 0.70 | CA1 (0.40) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22827920 | 0.70 | EDNRA (0.56) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL9754309 | 0.70 | CA1 (0.38) | CA1CA2CA9LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254697-A1 | FUSED 1,2 THIAZOLES AND 1,2 THIAZINES WHICH ACT AS NL3P3 MODULATORS | AC IMMUNE SA (CH) | 2020-12-24 | — | — | WO | disclosed |