Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 12/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22827908 | 0.72 | CA1 (0.38) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL1070351 | 0.71 | CA12 (0.61) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL13208390 | 0.70 | CA2 (0.48) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL30632216 | 0.65 | CA12 (0.53) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL619907 | 0.65 | CA12 (0.77) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL621753 | 0.65 | CA12 (0.53) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL30432593 | 0.65 | CA12 (0.53) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL8056782 | 0.65 | CA12 (0.53) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL2720902 | 0.65 | CA12 (0.48) | BDKRB1CA12CA1CA2CA7 | |
| SCHEMBL23523310 | 0.64 | CA12 (0.52) | BDKRB1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254697-A1 | FUSED 1,2 THIAZOLES AND 1,2 THIAZINES WHICH ACT AS NL3P3 MODULATORS | AC IMMUNE SA (CH) | 2020-12-24 | — | — | WO | disclosed |