Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22827968 | 0.87 | PTGS2 (0.54) | PTGS2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22827972 | 0.84 | PTGS2 (0.70) | PTGS2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22828089 | 0.84 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL22827914 | 0.83 | PTGS2 (0.65) | PTGS2KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL22827966 | 0.72 | PTGS2 (0.79) | PTGS2 | |
| SCHEMBL22828113 | 0.71 | PTGS2 (0.49) | PTGS2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL22827979 | 0.70 | KDM4E (0.54) | PTGS2KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL22828107 | 0.70 | ALDH1A1 (0.54) | PTGS2KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL22827970 | 0.70 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL24335035 | 0.68 | PTGS2 (1.00) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257653-A1 | RADIOLABELED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-12-24 | — | — | WO | disclosed |