Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.36 |
| ▸ | M6PR | P20645 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24212703 | 1.00 | LGALS8 (0.36) | LGALS8M6PRMEN1KMT2APPM1B | |
| SCHEMBL17267039 | 1.00 | LGALS8 (0.36) | LGALS8M6PRMEN1KMT2APPM1B | |
| SCHEMBL10291379 | 0.85 | PPM1B (0.36) | LGALS8M6PRMEN1KMT2APPM1B | |
| SCHEMBL17548801 | 0.85 | PPM1B (0.36) | LGALS8M6PRMEN1KMT2APPM1B | |
| SCHEMBL13640598 | 0.85 | PPM1B (0.36) | LGALS8M6PRMEN1KMT2APPM1B | |
| SCHEMBL9973799 | 0.85 | PPM1B (0.36) | LGALS8M6PRMEN1KMT2APPM1B | |
| SCHEMBL11956832 | 0.85 | PPM1B (0.36) | LGALS8M6PRMEN1KMT2APPM1B | |
| SCHEMBL22783853 | 0.85 | TLR4 (0.31) | M6PR | |
| SCHEMBL24212705 | 0.83 | MEN1 (0.31) | MEN1KMT2ASYNJ2 | |
| SCHEMBL21134683 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257235-A1 | 1-(4-(AMINOMETHYL)BENZYL)-2-BUTYL-2H-PYRAZOLO[3,4-C]QUINOLIN-4-AMINE DERIVATIVES AND RELATED COMPOUNDS AS TOLL-LIKE RECEPTOR (TLR) 7/8 AGONISTS, AS WELL AS ANTIBODY DRUG CONJUGATES THEREOF FOR USE IN CANCER THERAPY AND DIAGNOSIS | SUTRO BIOPHARMA, INC. (US) | 2020-12-24 | — | — | WO | disclosed |