SCHEMBL9973799

SCHEMBL9973799

COC(=O)[C@@H]1C[C@@H](O)[C@H](O)C(OC)O1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PPM1B O75688 1/20 0.36
▸ PTPN1 P18031 1/20 0.36
▸ PPP1CC P36873 1/20 0.36
▸ LGALS8 O00214 2/20 0.35
▸ CYP2C19 P33261 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ CHRNB2 P17787 1/20 0.31
▸ CHRNB4 P30926 1/20 0.31
▸ CHRNA3 P32297 1/20 0.31
▸ CHRNA7 P36544 1/20 0.31
▸ CHRNA4 P43681 1/20 0.31
▸ LGALS3 P17931 1/20 0.31
▸ M6PR P20645 2/20 0.30
▸ MGAM O43451 2/20 0.30
▸ SI P14410 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11956832 1.00 PPM1B (0.36) PPM1BPTPN1PPP1CCLGALS8CYP2C19
SCHEMBL17548801 1.00 PPM1B (0.36) PPM1BPTPN1PPP1CCLGALS8CYP2C19
SCHEMBL10291379 1.00 PPM1B (0.36) PPM1BPTPN1PPP1CCLGALS8CYP2C19
SCHEMBL13640598 1.00 PPM1B (0.36) PPM1BPTPN1PPP1CCLGALS8CYP2C19
SCHEMBL24212703 0.85 LGALS8 (0.36) PPM1BPTPN1PPP1CCLGALS8MEN1
SCHEMBL17267039 0.85 LGALS8 (0.36) PPM1BPTPN1PPP1CCLGALS8MEN1
SCHEMBL22828540 0.85 LGALS8 (0.36) PPM1BPTPN1PPP1CCLGALS8MEN1
SCHEMBL10258933 0.83 PPM1B (0.33) PPM1BPTPN1PPP1CCCYP2C19
SCHEMBL18869635 0.80 PPM1B (0.37) PPM1BPTPN1PPP1CCCYP2C19MEN1
SCHEMBL15883969 0.77 F10 (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120157407-A1 GALACTOSE-PRONGED POLYSACCHARIDES IN A FORMULATION FOR ANTIFIBROTIC THERAPIES PRO-PHARMACEUTICALS, INC. 2012-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157407-A1 GALACTOSE-PRONGED POLYSACCHARIDES IN A FORMULATION FOR ANTIFIBROTIC THERAPIES TPSG1, MMP1, COLGALT1 PPM1B 1600/4885PTPN1 1201/4885PPP1CC 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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