Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL27733580 | 0.84 | EGFR (0.52) | EGFRSRCKDRPI4KAPI4K2B | |
| SCHEMBL283730 | 0.82 | FGFR1 (0.51) | SRCPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1271540 | 0.78 | EGFR (0.61) | EGFRSRCKDRPI4KAPI4K2B | |
| Acetone SCHEMBL28162073 | 0.77 | CYP3A4 (0.47) | SRCPI4KAPI4K2BPI4K2API4KB | |
| Furan SCHEMBL28181037 | 0.76 | FGFR1 (0.44) | SRCFGFR1SLC22A6ADORA1CYP3A4 | |
| Adenine SCHEMBL22828945 | 0.74 | EGFR (0.41) | EGFRSRCKDRPI4KAPI4K2B | |
| Niacinamide SCHEMBL22748485 | 0.74 | EGFR (0.65) | EGFRSRCKDRPI4KAPI4K2B | |
| SCHEMBL27721221 | 0.72 | FGFR1 (0.47) | SRCFGFR1SLC22A6ADORA1CYP3A4 | |
| SCHEMBL1035726 | 0.72 | ENPP1 (0.51) | SRCFGFR1SLC22A6CYP3A4P2RY2 | |
| SCHEMBL21066915 | 0.72 | EGFR (0.65) | EGFRSRCKDRPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199639-B1 | NOVEL MEASUREMENT METHOD USING KINASE, AND COMPOSITION | ASAHI KASEI PHARMA CORP (JP) | 2020-12-30 | — | — | EP | claimed |