Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828946 | 0.84 | EGFR (0.53) | EGFRSRCKDRPI4KAPI4K2B | |
| SCHEMBL1035726 | 0.83 | ENPP1 (0.51) | SRCP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL502621 | 0.82 | ENPP1 (0.52) | SRCP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL8509835 | 0.82 | ENPP1 (0.50) | SRCP2RX3P2RX4P2RX2ENPP1 | |
| Niacinamide SCHEMBL22748485 | 0.80 | EGFR (0.65) | EGFRSRCKDRPI4KAPI4K2B | |
| Niacinamide SCHEMBL23531100 | 0.77 | EGFR (0.61) | EGFRSRCKDRPI4KAPI4K2B | |
| Niacinamide SCHEMBL28597484 | 0.77 | EGFR (0.61) | EGFRSRCKDRPI4KAPI4K2B | |
| SCHEMBL1271540 | 0.77 | EGFR (0.61) | EGFRSRCKDRPI4KAPI4K2B | |
| Triphosphate SCHEMBL19057041 | 0.77 | PI4KA (0.44) | EGFRSRCKDRPI4KAPI4K2B | |
| Adenosine Diphosphate SCHEMBL570243 | 0.76 | ADH1A (0.74) | SRCSIRT6P2RX3P2RX4P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101613672-A | Recombinant escherichia coli for preparing -4-chloro-3-hydroxybutanoate through asymmetric transformation and construction method thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2009-12-30 | — | — | CN | claimed |
| CN-103255183-A | Method for preparing (S)-ethyl 4-chloro-3-hydroxybutanoate through asymmetric reduction by use of carbonyl reductase and application thereof | NANJING CHANGXINJIA BIOTECHNOLOGY CO LTD | 2013-08-21 | — | — | CN | disclosed |
| CN-101372699-B | Application of carbonyl reductase in production of -4-chloro-3-hydroxy ethyl butyrate | NANJING TECH UNIVERSITY (CN) | 2011-11-30 | — | — | CN | disclosed |
| CN-101613672-A | Recombinant escherichia coli for preparing -4-chloro-3-hydroxybutanoate through asymmetric transformation and construction method thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2009-12-30 | — | — | CN | disclosed |
| CN-101372699-A | Application of carbonyl reductase in production of -4-chloro-3-hydroxy ethyl butyrate | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2009-02-25 | — | — | CN | disclosed |