Acetone

Acetone

SCHEMBL28162073

CC(C)=O.Nc1ncnc2c1ncn2OP(=O)(O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
FGFR1 P11362 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.47
AHCY P23526 4/20 0.47
ADORA1 P30542 6/20 0.46
ADORA2A P29274 4/20 0.46
GSK3B P49841 1/20 0.45
PI4KA P42356 3/20 0.43
PI4K2B Q8TCG2 3/20 0.43
PI4K2A Q9BTU6 3/20 0.43
PI4KB Q9UBF8 3/20 0.43
ADORA2B P29275 1/20 0.43
DNPH1 O43598 1/20 0.43
PRKAB2 O43741 1/20 0.43
TRPM2 O94759 1/20 0.43
LDHA P00338 1/20 0.43
ADRB2 P07550 1/20 0.43
FBP1 P09467 1/20 0.43
SRC P12931 1/20 0.43
P2RY2 P41231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283730 0.94 FGFR1 (0.51) CYP3A4FGFR1SLC22A6AHCYADORA1
Furan SCHEMBL28181037 0.85 FGFR1 (0.44) CYP3A4FGFR1SLC22A6ADORA1DNPH1
SCHEMBL1035726 0.83 ENPP1 (0.51) CYP3A4FGFR1SLC22A6SRCP2RY2
SCHEMBL27721221 0.83 FGFR1 (0.47) CYP3A4FGFR1SLC22A6AHCYADORA1
SCHEMBL9275563 0.82 ADORA2A (0.49) CYP3A4FGFR1SLC22A6AHCYADORA1
SCHEMBL8509835 0.82 ENPP1 (0.50) CYP3A4FGFR1SLC22A6ADORA1SRC
SCHEMBL502621 0.82 ENPP1 (0.52) FGFR1SLC22A6SRCP2RY2P2RY1
SCHEMBL27903676 0.80 CYP3A4 (0.47) CYP3A4FGFR1SLC22A6AHCYADORA1
SCHEMBL14125909 0.80 ADORA2A (0.51) CYP3A4AHCYADORA1ADORA2AGSK3B
SCHEMBL28406876 0.78 ADORA2A (0.50) CYP3A4AHCYADORA1ADORA2AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106900730-A A kind of plant growth regualting composition 江苏辉丰农化股份有限公司 2017-06-30 CN disclosed