SCHEMBL2282902

SCHEMBL2282902

COc1cccc(C=CC(=O)c2c(O)cc(O)cc2OC)c1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 7/20 0.88
▸ MAPT P10636 4/20 0.77
▸ KMT2A Q03164 4/20 0.77
▸ MEN1 O00255 3/20 0.77
▸ KCNA3 P22001 1/20 0.77
▸ NPSR1 Q6W5P4 1/20 0.77
▸ CYP3A4 P08684 4/20 0.71
▸ TP53 P04637 2/20 0.71
▸ ATM Q13315 1/20 0.71
▸ HSD17B10 Q99714 1/20 0.71
▸ TDP1 Q9NUW8 3/20 0.66
▸ KDM4E B2RXH2 2/20 0.66
▸ HPGD P15428 2/20 0.66
▸ NR1H4 Q96RI1 2/20 0.66
▸ CYP2C9 P11712 2/20 0.66
▸ CYP2C19 P33261 2/20 0.66
▸ CYP1A2 P05177 1/20 0.66
▸ CYP2D6 P10635 1/20 0.66
▸ MCL1 Q07820 1/20 0.66
▸ USP2 O75604 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382791 1.00 ABCG2 (0.88) ABCG2MAPTKMT2AMEN1KCNA3
SCHEMBL2282898 1.00 ABCG2 (0.88) ABCG2MAPTKMT2AMEN1KCNA3
SCHEMBL30383114 0.94 ABCG2 (1.00) ABCG2MAPTKMT2AMEN1KCNA3
SCHEMBL10850463 0.94 ABCG2 (1.00) ABCG2MAPTKMT2AMEN1KCNA3
SCHEMBL10850468 0.94 ABCG2 (1.00) ABCG2MAPTKMT2AMEN1KCNA3
SCHEMBL25194422 0.92 ABCG2 (0.79) ABCG2MAPTKMT2AMEN1KCNA3
SCHEMBL30382949 0.92 ABCG2 (0.79) ABCG2MAPTKMT2AMEN1KCNA3
SCHEMBL20472670 0.88 ABCG2 (0.85) ABCG2MAPTKMT2AMEN1CYP3A4
SCHEMBL20472672 0.88 ABCG2 (0.85) ABCG2MAPTKMT2AMEN1CYP3A4
SCHEMBL19182767 0.87 ABCG2 (0.79) ABCG2MAPTKMT2ACYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019528-A Compositions and methods for preventing and/or treating diseases associated with IL-23 expression ALLSPIM公司 2024-05-10 — — CN claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
CN-118019528-A Compositions and methods for preventing and/or treating diseases associated with IL-23 expression ALLSPIM公司 2024-05-10 — — CN disclosed
CN-118019528-A Compositions and methods for preventing and/or treating diseases associated with IL-23 expression ALLSPIM公司 2024-05-10 — — CN disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
US-9061984-B2 Compounds related to chalcones and benzothienopyrimidines, their synthesis, and uses to treat diseases UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2015-06-23 — — US disclosed
US-20110190325-A1 COMPOUNDS, THEIR SYNTHESES, AND THIER USES THE JOHNS HOPKINS UNIVERSITY 2011-08-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAPT 3297/4885KMT2A 2792/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAPT 3512/4885KMT2A 3188/4885
US-20110190325-A1 COMPOUNDS, THEIR SYNTHESES, AND THIER USES TERT, TYMS, NISCH ABCG2 1032/4885MAPT 2194/4885KMT2A 1587/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAPT 3512/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback