SCHEMBL228292

SCHEMBL228292

Brc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.67
CYP1A2 P05177 1/20 0.67
PTGS1 P23219 1/20 0.67
SLC6A2 P23975 1/20 0.67
CYP2C19 P33261 1/20 0.67
PTGS2 P35354 1/20 0.67
SLC6A3 Q01959 1/20 0.67
HIF1A Q16665 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
APP P05067 1/20 0.66
MAOB P27338 5/20 0.64
GAA P10253 1/20 0.64
MAPT P10636 1/20 0.64
MAOA P21397 1/20 0.64
RAB9A P51151 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
RXRA P19793 1/20 0.62
RXRB P28702 1/20 0.62
AR P10275 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4953 0.98 LMNA (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL12717358 0.94 LMNA (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL7665986 0.94 MCL1 (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8616107 0.94 MCL1 (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL11839266 0.92 APP (0.62) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL419232 0.91 MAOB (0.69) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL13903288 0.91 MAOB (0.59) LMNACYP1A2PTGS1SLC6A2CYP2C19
Formic Acid SCHEMBL28571007 0.89 RXRA (0.61) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL2399080 0.89 APP (0.80) APPMAOBMAOARXRARXRB
SCHEMBL339813 0.89 LMNA (0.82) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119191946-B Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide 南京工业大学 2026-05-15 CN claimed
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN claimed
CN-116253623-B Direct cross-coupling method of aryl fluorine sulfate and aryl bromine 南京工业大学 2024-04-05 CN claimed
CN-117106246-A High-resistance Wen Xiangsu fire-fighting boot and production process thereof 浙江恒诚鞋业有限公司 2023-11-24 CN claimed
CN-116721805-B Cable with flame-retardant high-temperature-resistant polyvinyl chloride sheath and extrusion molding process thereof 江苏锡缆特种线缆有限公司 2023-11-21 CN claimed
CN-116721805-A Cable with flame-retardant high-temperature-resistant polyvinyl chloride sheath and extrusion molding process thereof 江苏锡缆特种线缆有限公司 2023-09-08 CN claimed
CN-114591128-B Direct cross-coupling method of aryl sulfide salt and aryl bromide 南京工业大学 2023-08-22 CN claimed
CN-116554009-A Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide 南京工业大学 2023-08-08 CN claimed
CN-116283515-A Direct cross coupling method of aryl fluoride and aryl bromide 南京工业大学 2023-06-23 CN claimed
CN-116253623-A Direct cross-coupling method of aryl fluorine sulfate and aryl bromine 南京工业大学 2023-06-13 CN claimed
CN-114685251-B Direct cross-coupling reaction method of diaryl sulfoxide and aryl bromide 南京工业大学 2022-12-27 CN claimed
CN-112898133-B Preparation method of trans-ketone intermediate 河北迈尔斯通电子材料有限公司 2022-11-15 CN claimed
CN-114685251-A Direct cross-coupling reaction method of diaryl sulfoxide and aryl bromide 南京工业大学 2022-07-01 CN claimed
CN-114591128-A Direct cross-coupling method of aryl sulfur salt and aryl bromide 南京工业大学 2022-06-07 CN claimed
CN-113402350-A Biaryl compound and preparation method and application thereof 南京工业大学 2021-09-17 CN claimed
CN-112898133-A Preparation method of trans-ketone intermediate 河北迈尔斯通电子材料有限公司 2021-06-04 CN claimed
CN-106140383-B A kind of reworked material grinding device and its breaking method for sapphire kyropoulos 宁夏佳晶科技有限公司 2019-10-01 CN claimed
CN-105647515-B A kind of dendroid thermal activation delayed fluorescence material and its synthetic method 华南理工大学 2017-10-20 CN claimed
CN-106140383-A A kind of reworked material reducing mechanism for sapphire kyropoulos and breaking method thereof 宁夏佳晶科技有限公司 2016-11-23 CN claimed
CN-105647515-A Dendritic thermal activation delay fluorescence material and synthesizing method thereof 华南理工大学 2016-06-08 CN claimed