Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 1.00 |
| ▸ | MAPT | P10636 | 13/20 | 1.00 |
| ▸ | MEN1 | O00255 | 12/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | POLB | P06746 | 7/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | NSD2 | O96028 | 1/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22830597 | 1.00 | KMT2A (1.00) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL11155676 | 0.82 | MEN1 (0.70) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL5145115 | 0.81 | BRAF (0.68) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL5145120 | 0.81 | BRAF (0.68) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL13044214 | 0.80 | KMT2A (0.67) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL2492676 | 0.78 | MEN1 (0.80) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL2492673 | 0.78 | MEN1 (0.80) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL6397256 | 0.77 | BRAF (0.70) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL6396866 | 0.77 | BRAF (0.70) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL5163163 | 0.77 | MEN1 (0.61) | KMT2AMAPTMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12161630-B2 | Methods to control infection using new generation small molecule growth inhibitors | OHIO STATE INNOVATION FOUNDATION (US) | 2024-12-10 | — | — | US | disclosed |
| US-20230094112-A1 | METHODS TO CONTROL INFECTION USING NEW GENERATION SMALL MOLECULE GROWTH INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2023-03-30 | — | — | US | disclosed |
| US-11478454-B2 | Methods to control infection using new generation small molecule growth inhibitors | OHIO STATE INNOVATION FOUNDATION (US) | 2022-10-25 | — | — | US | disclosed |
| US-20200405691-A1 | METHODS TO CONTROL INFECTION USING NEW GENERATION SMALL MOLECULE GROWTH INHIBITORS | OHIO STATE INNOVATION FOUNDATION | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478454-B2 | Methods to control infection using new generation small molecule growth inhibitors | SMURF1, SMURF2, SMYD3 | KMT2A 3768/4885MAPT 4195/4885MEN1 1467/4885 |
| US-20230094112-A1 | METHODS TO CONTROL INFECTION USING NEW GENERATION SMALL MOLECULE GROWTH INHIBITORS | SMURF1, SMURF2, SMYD3 | KMT2A 3865/4885MAPT 4163/4885MEN1 1546/4885 |
| US-12161630-B2 | Methods to control infection using new generation small molecule growth inhibitors | SMURF1, SMURF2, SMYD3 | KMT2A 3768/4885MAPT 4195/4885MEN1 1467/4885 |
| US-20200405691-A1 | METHODS TO CONTROL INFECTION USING NEW GENERATION SMALL MOLECULE GROWTH INHIBITORS | SMURF1, SMURF2, SMYD3 | KMT2A 3768/4885MAPT 4195/4885MEN1 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.