Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | POLB | P06746 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.67 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.67 |
| ▸ | NSD2 | O96028 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396866 | 1.00 | BRAF (0.70) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL5145120 | 0.87 | BRAF (0.68) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL5145115 | 0.87 | BRAF (0.68) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL5163154 | 0.82 | MEN1 (0.61) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL5163163 | 0.82 | MEN1 (0.61) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL3760822 | 0.82 | PIK3CG (0.61) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL3760817 | 0.82 | PIK3CG (0.61) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL3760819 | 0.82 | PIK3CG (0.61) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL5147278 | 0.80 | BRAF (0.66) | BRAFMEN1KMT2AMAPTPOLB | |
| SCHEMBL6391636 | 0.80 | POLB (0.67) | BRAFMEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282840-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282840-A1 | Methods of modulating neurotrophin-mediated activity | NGF, BDNF, NTRK2 | BRAF 4079/4885MEN1 4004/4885KMT2A 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.