SCHEMBL2283117

SCHEMBL2283117

C1=CCC(c2ccccc2)(c2ccccc2)C=C1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.34
OPRM1 P35372 2/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
MAOB P27338 6/20 0.31
MAOA P21397 4/20 0.31
PNMT P11086 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
MEN1 O00255 1/20 0.30
CYP2C9 P11712 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL27402897 0.96 HDAC4 (0.32) HDAC4OPRM1OPRK1OPRL1
Biphenyl SCHEMBL28885424 0.94 ALDH1A1 (0.36) HDAC4MAOB
SCHEMBL30663214 0.89 KDM1A (0.36) HDAC4OPRM1OPRK1OPRL1MAOB
SCHEMBL30940607 0.86 SLC6A2 (0.36) HDAC4MAOA
SCHEMBL4630348 0.84 GRIN2B (0.33) OPRM1OPRK1OPRL1
SCHEMBL11881975 0.83
SCHEMBL7776293 0.79
SCHEMBL30149514 0.78 ALDH1A1 (0.38) OPRK1MEN1KMT2A
SCHEMBL28146651 0.78 ESR2 (0.39) MEN1KMT2A
SCHEMBL28088792 0.78 HDAC4 (0.31) HDAC4OPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566894-B Potent inhibitors of D-amino acid oxidase (DAAO) and uses thereof 心悦生医股份有限公司 2025-01-17 CN disclosed
CN-116325004-A Information processing device, information processing method, and program 味之素株式会社 2023-06-23 CN disclosed
CN-115872821-A Application of Pd-loaded polyaniline catalyst in catalysis of suzuki coupling reaction 枣庄学院 2023-03-31 CN disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
CN-109415521-A Functional film, polarizing plate and display device 富士胶片株式会社 2019-03-01 CN disclosed
CN-109415465-A Copolymer and composition 富士胶片株式会社 2019-03-01 CN disclosed
US-8003837-B2 Iron oxide catalyst with hematite, potassium ferrite BASF SE (DE) 2011-08-23 US disclosed
US-20080200739-A1 Catalyst For the Dehydrogenation or Hydrogenation of Hydrocarbons Containing Secondary Catalyst BASF AKTIENGESELLSCHAFT (DE) 2008-08-21 US disclosed
CN-1831569-A Anisotropic scattering sheet DAICEL CHEM (JP) 2006-09-13 CN disclosed
US-20050124837-A1 Preparation of alkenylaromatic compounds BASF AKTIENGESELLSCHAFT (DE) 2005-06-09 US disclosed
EP-1470095-A1 METHOD FOR PRODUCING ALKENYL AROMATIC COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2004-10-27 EP disclosed
WO-2003062175-A1 METHOD FOR PRODUCING ALKENYL AROMATIC COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2003-07-31 WO disclosed
CN-1097074-C Thermoplastic resin composition DAICEL CHEM (JP) 2002-12-25 CN disclosed
CN-1206027-A Thermoplastic resin composition DAICEL CHEM (JP) 1999-01-27 CN disclosed
CN-1203246-A Thermoplastic resin composition DAICEL CHEM (JP) 1998-12-30 CN disclosed
US-4626497-A PHOTOPOLYMERIZABLE ADDITION POLYMER WITH PENDANT MALEIMIDE GROUPS CIBA-GEIGY AG (CH) 1986-12-02 US disclosed