SCHEMBL7776293

SCHEMBL7776293

O=C1NC(C2(c3ccccc3)C=CC=CC2)=C2C(=O)NC(C3(c4ccccc4)C=CC=CC3)=C12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2283117 0.79 HDAC4 (0.34)
Ethylene SCHEMBL27402897 0.76 HDAC4 (0.32)
Biphenyl SCHEMBL28885424 0.74 ALDH1A1 (0.36)
SCHEMBL6706514 0.71
SCHEMBL30663214 0.70 KDM1A (0.36)
SCHEMBL11881975 0.69
SCHEMBL7497546 0.69 HDAC4 (0.31)
SCHEMBL30940607 0.68 SLC6A2 (0.36)
SCHEMBL27636806 0.67 MTOR (0.34)
SCHEMBL4630348 0.67 GRIN2B (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719842-B1 Pigment compositions for coatings CIBA SC HOLDING AG (CH) 2001-09-05 EP claimed
EP-0719842-A2 Pigment compositions for coatings CIBA-GEIGY AG (CH) 1996-07-03 EP claimed
EP-1137390-A1 COSMETIC PREPARATIONS CONTAINING ORGANIC PIGMENTS FROM THE CLASS OF PYRROLO- 3,4-C]-PYRROLES Ciba SC Holding AG (CH) 2001-10-04 EP disclosed
EP-0719842-B1 Pigment compositions for coatings CIBA SC HOLDING AG (CH) 2001-09-05 EP disclosed
WO-2000033795-A1 COSMETIC PREPARATIONS CONTAINING ORGANIC PIGMENTS FROM THE CLASS OF PYRROLO-[3,4-C]-PYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-06-15 WO disclosed
EP-0719842-A2 Pigment compositions for coatings CIBA-GEIGY AG (CH) 1996-07-03 EP disclosed