SCHEMBL22831353

SCHEMBL22831353

Cc1cc(OCCN(C)CCOc2cc(C)nc(C)c2)cc(C)n1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 3/20 0.46
▸ MAPT P10636 1/20 0.44
▸ LMNA P02545 1/20 0.43
▸ ALDH1A1 P00352 3/20 0.42
▸ CHRNB2 P17787 2/20 0.41
▸ CHRNA4 P43681 2/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ CASP1 P29466 1/20 0.40
▸ CASP7 P55210 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22831349 0.88 MAPT (0.58) MAPTALDH1A1CHRNB2CHRNA4
SCHEMBL22831325 0.79 KCNH2 (0.53) KCNH2MAPTLMNAALDH1A1CHRNB2
SCHEMBL23074715 0.77 ALDH1A1 (0.36) ALDH1A1L3MBTL1
SCHEMBL23074667 0.75 ALDH1A1 (0.46) MAPTLMNAALDH1A1L3MBTL1CASP1
SCHEMBL22831350 0.73 MAPT (0.46) KCNH2MAPTLMNACHRNB2CHRNA4
SCHEMBL23067906 0.73 DRD2 (0.50) ALDH1A1CASP1CASP7HSD17B10
SCHEMBL2127322 0.73 ALDH1A1 (0.41) KCNH2MAPTLMNAALDH1A1L3MBTL1
SCHEMBL22831354 0.72 MAPT (0.44) KCNH2MAPTLMNACHRNB2CHRNA4
SCHEMBL23067921 0.72 HTR1B (0.52) LMNAALDH1A1CHRNB2CHRNA4CASP1
SCHEMBL11308063 0.72 SMN1; SMN2 (0.49) MAPTLMNAALDH1A1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115318256-A Anion exchange-hydrophobic mixed mode chromatography resin 生物辐射实验室股份有限公司 2022-11-11 — — CN claimed
CN-111818980-B Anion exchange-hydrophobic mixed mode chromatography resins 生物辐射实验室股份有限公司 2022-10-11 — — CN claimed
US-12343702-B2 Anionic exchange-hydrophobic mixed mode chromatography resin BIO-RAD LABORATORIES, INC. (US) 2025-07-01 — — US disclosed
US-20250196100-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN BIO-RAD LABORATORIES, INC. 2025-06-19 — — US disclosed
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2021-03-11 — — US disclosed
US-20200406232-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN BIO-RAD LABORATORIES, INC. 2020-12-31 — — US disclosed
US-20200406232-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN BIO-RAD LABORATORIES, INC. 2020-12-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200406232-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN FCGRT, PBRM1, BCR KCNH2 3145/4885MAPT 965/4885LMNA 2975/4885
US-20210069692-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 KCNH2 1383/4885MAPT 4182/4885LMNA 1875/4885
US-20250196100-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN SLC7A1, ABCG2, MSR1 KCNH2 1420/4885MAPT 4015/4885LMNA 2514/4885
US-12343702-B2 Anionic exchange-hydrophobic mixed mode chromatography resin FCGRT, PBRM1, BCR KCNH2 3145/4885MAPT 965/4885LMNA 2975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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