Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL527230 | 0.95 | CA1 (0.31) | CA1CA2MEN1APAF1RGS12 | |
| SCHEMBL329178 | 0.89 | HTT (0.35) | CA1CA2MEN1RGS12HSP90AA1 | |
| SCHEMBL15549268 | 0.89 | CA1 (0.31) | CA1CA2 | |
| Phosphoric Acid SCHEMBL14164747 | 0.88 | GGPS1 (0.31) | HTT | |
| Water SCHEMBL15571107 | 0.88 | HTT (0.34) | CA1CA2MEN1RGS12HSP90AA1 | |
| Bromide SCHEMBL204549 | 0.88 | CA1 (0.36) | CA1CA2MEN1RGS12HSP90AA1 | |
| Iodide SCHEMBL1226177 | 0.88 | HTT (0.35) | CA1CA2MEN1RGS12HSP90AA1 | |
| Hydrochloric Acid SCHEMBL202419 | 0.88 | HTT (0.34) | CA1CA2MEN1RGS12HSP90AA1 | |
| Sulfuric Acid SCHEMBL21331906 | 0.87 | KDM4E (0.33) | HTT | |
| Perchlorate SCHEMBL31677386 | 0.86 | CA1 (0.33) | CA1CA2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836849-B | Process for producing fibers, films and moldings of polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3512905-B1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2022-08-24 | — | — | EP | disclosed |
| US-20200407508-A1 | METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) | BASF SE (DE) | 2020-12-31 | — | — | US | disclosed |
| CN-111836849-A | Process for producing fibers, films and moldings of polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2020-10-27 | — | — | CN | disclosed |